Shedding New Light on Cancer Metabolism: A Metabolic Tightrope Between Life and Death
Since the earliest findings of Otto Warburg, who discovered the first metabolic differences between lactate production of cancer cells and non-malignant tissues in the 1920s, much time has passed.He explained the increased lactate levels with dysfunctional mitochondria and aerobic glycolysis despite adequate oxygenation.Meanwhile, we came to know t